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Fosaprepitant dimeglumine

neurokinin-1 receptor 拮抗剂

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产品目录号: A11069


产品名 目录号 价格 数量
Fosaprepitant dimeglumine 5mg A11069-5
¥ 800.00
Fosaprepitant dimeglumine 10mg A11069-10
¥ 1,400.00
Fosaprepitant dimeglumine 25mg A11069-25
¥ 2,600.00
Fosaprepitant dimeglumine 10mM * 1mL in DMSO A11069-10mM-D
¥ 2,200.00



Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antagonist.

Fosaprepitant dimeglumine




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11069
Mechanism of action Antagonist
分子量 1004.84
化学分子式 C37H56F7N6O16P
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 265121-04-8
Synonyms MK 0517
SMILES code C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
化学名称 [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol


Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antagonist.
NK-1 receptor


Solubility (25°C)* In vitro DMSO 201 mg/mL (200.03 mM)
Water 135 mg/mL (134.35 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.95 mL 49.76 mL 99.52mL
0.5 mM 1.99 mL 9.95 mL 19.9 mL
1 mM 1 mL 4.98 mL 9.95 mL
5 mM 0.2 mL 1 mL 1.99 mL

*The above data is based on the productmolecular weight 1004.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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