FR 180204

目录号: A14119

ERK inhibitor

FR 180204

FR 180204 Chemical Structure

CAS NO. 865362-74-9

FR 180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 950.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

FR 180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.
Targets
ERK2 ERK1
0.14 μM(Ki)0.31 μM(Ki)
In vitro DMSO 65 mg/mL (198.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL heating (6.1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.55 mL 152.75 mL 305.49 mL
0.5 mM 6.11 mL 30.55 mL 61.1 mL
1 mM 3.05 mL 15.27 mL 30.55 mL
5 mM 0.61 mL 3.05 mL 6.11 mL

*The above data is based on the productmolecular weight 327.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14119
MECHANISM OF ACTION Inhibitor
M. Wt 327.34
Formula C18H13N7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 865362-74-9
Synonyms FR-180204,FR180204
SMILES C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=CC5=C(NN=C5N=N4)N

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