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PAK 抑制剂

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产品目录号: A13691


产品名 目录号 价格 数量
FRAX486 10mg A13691-10
¥ 1,200.00
FRAX486 25mg A13691-25
¥ 2,500.00
FRAX486 50mg A13691-50
¥ 4,000.00



FRAX486 is a small-molecule PAK inhibitor.





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Chemical Information

目录号 A13691
Mechanism of action Inhibitor
分子量 513.39
化学分子式 C25H23Cl2FN6O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1232030-35-1
Synonyms FRAX 486, FRAX-486
SMILES code CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F
化学名称 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one


FRAX486 is a small-molecule PAK inhibitor.
14 nM33 nM39 nM575 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.48 mL 97.39 mL 194.78mL
0.5 mM 3.9 mL 19.48 mL 38.96 mL
1 mM 1.95 mL 9.74 mL 19.48 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 513.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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