FRAX486

Name: FRAX486
SKU: A13691

目录号: A13691

PAK 抑制剂

Product Citations (1)

FRAX486 Chemical Structure

CAS NO. 1232030-35-1

FRAX486是一种小分子PAK抑制剂。

库存：现货

规格	价格	数量
10 mg	￥ 1,200.00
25 mg	￥ 2,500.00
50 mg	￥ 4,000.00

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生物活性

FRAX486是一种小分子PAK抑制剂。

靶点信息

PAK1	PAK2	PAK3	PAK4
14 nM	33 nM	39 nM	575 nM

溶解度 *

In vitro	DMSO	21 mg/mL (40.9 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.48 mL	97.39 mL	194.78 mL
0.5 mM	3.9 mL	19.48 mL	38.96 mL
1 mM	1.95 mL	9.74 mL	19.48 mL
5 mM	0.39 mL	1.95 mL	3.9 mL

*The above data is based on the productmolecular weight 513.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13691
作用机制	Inhibitor (抑制剂)
M. Wt	513.39
Formula	C25H23Cl2FN6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1232030-35-1
Synonyms	FRAX 486, FRAX-486
SMILES	CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F