Freselestat (ONO-6818)

目录号: A12780

neutrophil elastase 抑制剂

Freselestat (ONO-6818)

Freselestat (ONO-6818) Chemical Structure

CAS NO. 208848-19-5

Freselestat是一种有效的嗜中性粒细胞弹性蛋白酶抑制剂。 在模拟体外循环过程中,Freselestat减少了炎症介质。 ONO-6818显着降低了白介素8和C5b-9的产量。 在再循环期间,ONO-6818不能调节CD11b和L-选择素的变化。

库存: 现货

规格 价格 数量
5 mg
¥ 4,500.00
10 mg
¥ 8,500.00
25 mg
¥ 16,000.00
50 mg
¥ 30,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Freselestat是一种有效的嗜中性粒细胞弹性蛋白酶抑制剂。 在模拟体外循环过程中,Freselestat减少了炎症介质。 ONO-6818显着降低了白介素8和C5b-9的产量。 在再循环期间,ONO-6818不能调节CD11b和L-选择素的变化。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.1 mL 110.49 mL 220.99 mL
0.5 mM 4.42 mL 22.1 mL 44.2 mL
1 mM 2.21 mL 11.05 mL 22.1 mL
5 mM 0.44 mL 2.21 mL 4.42 mL

*The above data is based on the productmolecular weight 452.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12780
作用机制 Inhibitor (抑制剂)
M. Wt 452.51
Formula C23H28N6O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 208848-19-5
Synonyms ONO6818, ONO 6818
SMILES C3=C(C1=NC=C(C(N1CC(NC(C(C2=NN=C(O2)C(C)(C)C)=O)C(C)C)=O)=O)N)C=CC=C3

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