Fruquintinib
目录号: A14393
VEGFR 抑制剂
Fruquintinib 是一种口服可用的小分子抑制剂,针对血管内皮生长因子受体(VEGFRs),具有潜在的抗血管生成和抗肿瘤活性。
Discription | Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities. | ||
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Targets |
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目录号 | A14393 |
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分子式 | C21H19N3O5 |
分子量 | 393.3927 |
CAS号 | 1194506-26-7 |
SMILES | O=C(C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12)NC |
其他名称 | HMPL-013, HMPL 013, HMPL013 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 6 mg/mL (15.25 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.42 mL | 127.1 mL | 254.2 mL |
0.5 mM | 5.08 mL | 25.42 mL | 50.84 mL |
1 mM | 2.54 mL | 12.71 mL | 25.42 mL |
5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2