FTI-277 HCl

Name: FTI-277 HCl
SKU: A14439
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A14439

FTase 抑制剂

FTI-277 HCl 是一种法尼基转移酶（FTase）抑制剂；它是一种高效的 Ras CAAX 肽类模拟物，能够拮抗 H- 和 K-Ras 的致癌信号传导。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥595.00	现货
10mg	¥1,015.00	现货
25mg	¥2,065.00	现货
50mg	¥3,920.00	现货
100mg	¥5,495.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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Data Sheet

SDS

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生物活性

Discription

FTI-277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.

Targets

Target	Value

产品信息

目录号	A14439
分子式	C22H30ClN3O3S2
分子量	484.07
CAS号	180977-34-8
SMILES	COC(=O)[C@H](CCSC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2.Cl
其他名称	FTI 277, FTI277
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (185.92 mM)
	Water	16 mg/mL (33.04 mM)
	Ethanol	Warmed: 13 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.66 mL	103.29 mL	206.58 mL
0.5 mM	4.13 mL	20.66 mL	41.32 mL
1 mM	2.07 mL	10.33 mL	20.66 mL
5 mM	0.41 mL	2.07 mL	4.13 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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