FTI-277 HCl

目录号: A14439

FTase Inhibitor

FTI-277 HCl

FTI-277 HCl Chemical Structure

CAS NO. 180977-34-8

FTI-277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

FTI-277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.
Targets
FTase GGTase I
500 pM50 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.66 mL 103.29 mL 206.58 mL
0.5 mM 4.13 mL 20.66 mL 41.32 mL
1 mM 2.07 mL 10.33 mL 20.66 mL
5 mM 0.41 mL 2.07 mL 4.13 mL

*The above data is based on the productmolecular weight 484.07. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14439
MECHANISM OF ACTION Inhibitor
M. Wt 484.07
Formula C22H30ClN3O3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 180977-34-8
Synonyms FTI 277, FTI277
SMILES COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2.Cl.Cl

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