Fulacimstat
目录号: A19202
chymase 抑制剂
Fulacimstat 是一种可口服的 chymase 抑制剂,对人类和仓鼠的 chymase 酶 的 IC50 分别为 4, 3 nM。
| Discription | Fulacimstat is an orally available chymase inhibitor, with IC50s of 4, 3 nM for human and hamster chymase enzyme, respectively. |
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| 目录号 | A19202 |
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| 分子式 | C23H16F3N3O6 |
| 分子量 | 487.38 |
| CAS号 | 1488354-15-9 |
| SMILES | O=C(N(C1=CC=C(N2C)C(OC2=O)=C1)C=C(C(O)=O)C3=O)N3[C@H]4C5=CC=CC(C(F)(F)F)=C5CC4 |
| 其他名称 | BAY1142524, BAY 1142524, BAY-1142524 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 88 mg/mL (188.05mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.52 mL | 102.59 mL | 205.18 mL |
| 0.5 mM | 4.1 mL | 20.52 mL | 41.04 mL |
| 1 mM | 2.05 mL | 10.26 mL | 20.52 mL |
| 5 mM | 0.41 mL | 2.05 mL | 4.1 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2