Fumagillin

Name: Fumagillin
SKU: A15299

目录号: A15299

Aminopeptidase 抑制剂

Fumagillin Chemical Structure

CAS NO. 23110-15-8

Fumagillin是一种复杂的天然产物抗生素，它与II型蛋氨酸氨基肽酶（MetAP-2）的关键组氨酸残基共价结合，抑制内皮细胞增殖和血管生成。

库存：现货

规格	价格	数量
1 mg	￥ 550.00
5 mg	￥ 2,100.00
10 mg	￥ 4,800.00

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生物活性

Fumagillin是一种复杂的天然产物抗生素，它与II型蛋氨酸氨基肽酶（MetAP-2）的关键组氨酸残基共价结合，抑制内皮细胞增殖和血管生成。

靶点信息

MetAP2

溶解度 *

In vitro	DMSO	86 mg/mL (187.55 mM)
	Water	Insoluble
	Ethanol	Warmed: 30 mg/mL (65.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.81 mL	109.04 mL	218.08 mL
0.5 mM	4.36 mL	21.81 mL	43.62 mL
1 mM	2.18 mL	10.9 mL	21.81 mL
5 mM	0.44 mL	2.18 mL	4.36 mL

*The above data is based on the productmolecular weight 458.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15299
作用机制	Inhibitor (抑制剂)
M. Wt	458.55
Formula	C26H34O7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	23110-15-8
SMILES	CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C