G-418 disulfate
目录号: A21002
G-418(硫酸盐)是一种与庆大霉素B1结构相似的氨基糖苷类抗生素,它通过抑制原核和真核细胞中的延伸步骤来阻断多肽合成。
Discription | G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. | ||
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目录号 | A21002 |
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分子式 | C20H44N4O18S2 |
分子量 | 692.71 |
CAS号 | 108321-42-2 |
SMILES | O=S(O)(O)=O.O[C@@H]([C@@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)N)([H])O[C@]2([H])[C@H](O)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O.O=S(O)(O)=O |
其他名称 | Geneticin sulfate; Antibiotic G-418 sulfate, G418, G 418 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Insoluble | |
Water | Warmed: 92 mg/mL (132.81 mM) | ||
Ethanol | Insoluble | ||
In vivo | Saline | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 14.44 mL | 72.18 mL | 144.36 mL |
0.5 mM | 2.89 mL | 14.44 mL | 28.87 mL |
1 mM | 1.44 mL | 7.22 mL | 14.44 mL |
5 mM | 0.29 mL | 1.44 mL | 2.89 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2