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G-479

MEK 抑制剂

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产品目录号: A14380

库存状态:中国现货中国现货

产品名 目录号 价格 数量
G-479 2mg A14380-2
¥ 2,000.00
G-479 5mg A14380-5
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

G-479 is an potent MEK inhibitor. G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.

G-479

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Chemical Information

目录号 A14380
Mechanism of action Inhibitor
分子量 487.22
化学分子式 C16H15FIN5O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1168092-22-5
Synonyms G479, G 479
SMILES code O=C(C1=C(NC2=CC=C(I)C=C2F)N3C(C=N1)=CN=C3)NOC[C@H](O)CO
化学名称 (R)-N-(2,3-dihydroxypropoxy)-5-((2-fluoro-4-iodophenyl)amino)imidazo[1,5-a]pyrazine-6-carboxamide

生物活性

Description
G-479 is an potent MEK inhibitor. G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.52 mL 102.62 mL 205.25mL
0.5 mM 4.1 mL 20.52 mL 41.05 mL
1 mM 2.05 mL 10.26 mL 20.52 mL
5 mM 0.41 mL 2.05 mL 4.1 mL

*The above data is based on the productmolecular weight 487.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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