G007-LK

Name: G007-LK
SKU: A15528
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A15528

TNKS 抑制剂

1 篇发表文献

G007-LK 对 tankyrases 1 和 2 表现出高度选择性，其生化 IC50 值分别为 46 nM 和 25 nM，细胞 IC50 值为 50 nM，并且在小鼠中具有优异的药代动力学特性。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥385.00	现货
5mg	¥525.00	现货
10mg	¥945.00	现货
25mg	¥2,065.00	现货
50mg	¥3,850.00	现货
100mg	¥5,460.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用G007-LK发表的1篇文献

Dominic B. Bernkopf, .et al. , Nat Commun, 2019, 10:4251 PMID: 31534175

生物活性

Discription

G007-LK displays high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice,

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15528
分子式	C25H16ClN7O3S
分子量	529.96
CAS号	1380672-07-0
SMILES	CS(=O)(=O)C1=CN=C(C=C1)C2=NN=C(N2C3=CC=CC=C3Cl)C=CC4=NN=C(O4)C5=CC=C(C=C5)C#N
其他名称	G007 LK, G007LK
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	98 mg/mL (184.92 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.87 mL	94.35 mL	188.69 mL
0.5 mM	3.77 mL	18.87 mL	37.74 mL
1 mM	1.89 mL	9.43 mL	18.87 mL
5 mM	0.38 mL	1.89 mL	3.77 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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