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G907

G907

Name: G907
SKU: A18540

目录号: A18540

ABC transporter antagonist

G907 Chemical Structure

CAS NO. 2244035-16-1

G907 is a selective small-molecule antagonist of ATP-binding cassette (ABC) transporter, MsbA. It inhibits purified E. coli MsbA in amphipols with an IC50 of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket. Bactericidal activity.

库存：现货

规格	价格	数量
5 mg	￥ 3,500.00
10 mg	￥ 6,500.00
50 mg	￥ 20,000.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.05 mL	115.23 mL	230.45 mL
0.5 mM	4.61 mL	23.05 mL	46.09 mL
1 mM	2.3 mL	11.52 mL	23.05 mL
5 mM	0.46 mL	2.3 mL	4.61 mL

*The above data is based on the productmolecular weight 433.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18540
作用机制	Antagonist (拮抗剂)
M. Wt	433.93
Formula	C26H24ClNO3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2244035-16-1
Synonyms	G-907, G 907
SMILES	O=C(O)/C=C/C1=C(C2CC2)C3=CC(OC(C4=C(C5CC5)C=CC=C4Cl)C)=CC=C3N=C1