Galiximab (IDEC 114) is a primatized monoclonal antibody of the immunoglobulin G1 (IgG1) lambda class, specifically targeting the CD80 antigen to inhibit the CD80-CD28 interaction. This antibody features variable regions derived from cynomolgus monkeys and human constant regions. Galiximab is commonly utilized in the study of B-cell lymphoma, providing a valuable tool for investigating the role of CD80 in immune modulation and cancer biology.
Galiximab (IDEC 114) is a primatized monoclonal antibody of the immunoglobulin G1 (IgG1) lambda class, specifically targeting the CD80 antigen to inhibit the CD80-CD28 interaction. This antibody features variable regions derived from cynomolgus monkeys and human constant regions. Galiximab is commonly utilized in the study of B-cell lymphoma, providing a valuable tool for investigating the role of CD80 in immune modulation and cancer biology.
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