Gambogenic acid

Name: Gambogenic acid
SKU: A22383
Price: 595 CNY
Rating: 5 (288 reviews)

目录号: A22383

EZH2 抑制剂

Gambogenic acid 是藤黄中的活性成分，具有抗癌活性。Gambogenic acid 作为 EZH2 的有效抑制剂，特异性并共价地结合到 EZH2-SET 领域内的 Cys668，并诱导 EZH2 泛素化。

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Grouped product items
规格	价格	库存
1mg	¥595.00	现货
5mg	¥840.00	现货
10mg	¥1,435.00	现货
25mg	¥2,660.00	现货
50mg	¥5,040.00	现货
100mg	¥8,225.00	现货
*10mM 1mL in DMSO**	¥2,030.00	现货
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Data Sheet

SDS

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生物活性

Discription

Gambogenic acid is an active ingredient in gamboge, with anticancer activity. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A22383
分子式	C38H46O8
分子量	630.77
CAS号	173932-75-7
SMILES	O=C(O)/C(C)=C\C[C@@]1(C2=O)OC(C)(C)[C@]([C@]31OC4=C5C(O)=C(C/C=C(C)/CC/C=C(C)\C)C(O)=C4C/C=C(C)\C)([H])C[C@@]2([H])C=C3C5=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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