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Ganetespib (STA-9090)

促销

Hsp90 抑制剂

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产品目录号: A11402

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Ganetespib 50mg A11402-50
¥ 2,400.00
Ganetespib 100mg A11402-100
¥ 4,400.00
Ganetespib 5mg A11402-5
¥ 700.00
Ganetespib 10mg A11402-10
¥ 1,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer.

Ganetespib (STA-9090)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Ganetespib (STA-9090) 发表的文献 (2)
  • Yamada-Kanazawa S, .et al. Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway, Br J Dermatol, 2017, Aug;177(2):456-469 PMID: 28078663
  • Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107每113

Chemical Information

目录号 A11402
Mechanism of action Inhibitor
分子量 364.4
化学分子式 C20H20N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 888216-25-9
Synonyms STA9090
SMILES code CC(C)C1=CC(=C2NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)C(=O)C=C1O
化学名称 5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H- 1,2,4-triazol-3-one

生物活性

Description
Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer.
Targets
HSP90 (OSA 8 cells)
4 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.44 mL 137.21 mL 274.42mL
0.5 mM 5.49 mL 27.44 mL 54.88 mL
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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