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GANT61

目录号: A13252
GLI 拮抗剂
GANT61 是一种抑制剂,针对 GLI1 以及 GLI2 引发的转录,抑制 hedgehog 信号通路,IC50 为 5 微摩尔,显示出对其他途径的选择性,如 TNF糖皮质激素受体 基因激活。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥315.00
现货
10mg
¥490.00
现货
25mg
¥1,015.00
现货
50mg
¥1,925.00
现货
100mg
¥3,115.00
现货
500mg
¥7,315.00
现货
10mM * 1mL in DMSO
¥385.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用GANT61发表的3篇文献
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Cheng Zhou, .et al. , Cell Death Dis, 2021, Mar 3;12(3):231 PMID: 33658491
  • Hui Liang, .et al. , Sci Rep, 2017, 7: 40361 PMID: 28098170
  • 生物活性
    Discription GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A13252
    分子式 C27H35N5
    分子量 429.61
    CAS号 500579-04-4
    SMILES CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C
    其他名称 NSC136476, NSC-136476, GANT 61, GANT-61
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO Insoluble
    Water Insoluble
    Ethanol 11 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.28 mL 116.38 mL 232.77 mL
    0.5 mM 4.66 mL 23.28 mL 46.55 mL
    1 mM 2.33 mL 11.64 mL 23.28 mL
    5 mM 0.47 mL 2.33 mL 4.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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