GANT61

Name: GANT61
SKU: A13252

目录号: A13252

GLI 拮抗剂

Product Citations (2)

GANT61 Chemical Structure

CAS NO. 500579-04-4

GANT61是GLI1和GLI2诱导的转录的抑制剂，以5μM的IC50抑制hedgehog，对其他途径（例如TNF和糖皮质激素受体基因反式激活）表现出选择性。

库存：现货

规格	价格	数量
10 mg	￥ 750.00
25 mg	￥ 1,500.00
50 mg	￥ 2,800.00
100 mg	￥ 4,800.00
10mM * 1mL in DMSO	￥ 550.00

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生物活性

GANT61是GLI1和GLI2诱导的转录的抑制剂，以5μM的IC50抑制hedgehog，对其他途径（例如TNF和糖皮质激素受体基因反式激活）表现出选择性。

靶点信息

GLI1 (HEK293T cells expressing GLI1)
5 μM

溶解度 *

In vitro	DMSO	Insoluble
	Water	Insoluble
	Ethanol	11 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.28 mL	116.38 mL	232.77 mL
0.5 mM	4.66 mL	23.28 mL	46.55 mL
1 mM	2.33 mL	11.64 mL	23.28 mL
5 mM	0.47 mL	2.33 mL	4.66 mL

*The above data is based on the productmolecular weight 429.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13252
作用机制	Antagonist (拮抗剂)
M. Wt	429.61
Formula	C27H35N5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	500579-04-4
Synonyms	NSC136476, NSC-136476, GANT 61, GANT-61
SMILES	CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C