Garivulimab (BGB-A333) is a humanized IgG1-variant monoclonal antibody engineered to specifically target and bind to the programmed death-ligand 1 (PD-L1). This antibody selectively inhibits the interaction between PD-L1 and its receptor, programmed death-1 (PD-1), a critical pathway exploited by tumors to evade immune detection. Through this mechanism, Garivulimab exhibits potent antitumor activity, making it a valuable tool for cancer immunotherapy research.
Garivulimab (BGB-A333) is a humanized IgG1-variant monoclonal antibody engineered to specifically target and bind to the programmed death-ligand 1 (PD-L1). This antibody selectively inhibits the interaction between PD-L1 and its receptor, programmed death-1 (PD-1), a critical pathway exploited by tumors to evade immune detection. Through this mechanism, Garivulimab exhibits potent antitumor activity, making it a valuable tool for cancer immunotherapy research.
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