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GDC-0032 (Taselisib)


PI3K 抑制剂

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产品目录号: A12831


产品名 目录号 价格 数量
GDC-0032 5mg A12831-5
¥ 700.00
GDC-0032 10mg A12831-10
¥ 1,100.00
GDC-0032 25mg A12831-25
¥ 2,000.00
GDC-0032 50mg A12831-50
¥ 2,900.00



GDC-0032 is a potent, next-generation PI3 inhibitor targeting PI3 alpha.

GDC-0032 (Taselisib)




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Chemical Information

目录号 A12831
Mechanism of action Inhibitor
分子量 460.53
化学分子式 C24H28N8O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1282512-48-4
Synonyms GDC 0032, GDC0032
SMILES code CC1=NN(C(=N1)C2=CN3CCOC4=C(C3=N2)C=CC(=C4)C5=CN(N=C5)C(C)(C)C(=O)N)C(C)C


GDC-0032 is a potent, next-generation PI3 inhibitor targeting PI3 alpha.
Target Value
PI3Kδki: 0.12nM
PI3Kαki: 0.29nM
PI3Kγki: 0.97nM
PI3Kβki: 9.1nM
C2βIC50: 292nM
hVps34IC50: 374nM
mTORki: 1.2μM
DNA-PKIC50: >4.8μM
C2αIC50: >10μM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.71 mL 108.57 mL 217.14mL
0.5 mM 4.34 mL 21.71 mL 43.43 mL
1 mM 2.17 mL 10.86 mL 21.71 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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