GDC-0032 (Taselisib)

目录号: A12831

PI3K inhibitor

GDC-0032 (Taselisib) Chemical Structure

CAS NO. 1282512-48-4

GDC-0032 is a potent, next-generation PI3 inhibitor targeting PI3 alpha.

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,100.00
25 mg
¥ 2,000.00
50 mg
¥ 2,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GDC-0032 is a potent, next-generation PI3 inhibitor targeting PI3 alpha.
Targets
Target Value
PI3Kδki: 0.12nM
PI3Kαki: 0.29nM
PI3Kγki: 0.97nM
PI3Kβki: 9.1nM
C2βIC50: 292nM
hVps34IC50: 374nM
mTORki: 1.2μM
DNA-PKIC50: >4.8μM
C2αIC50: >10μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.71 mL 108.57 mL 217.14 mL
0.5 mM 4.34 mL 21.71 mL 43.43 mL
1 mM 2.17 mL 10.86 mL 21.71 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12831
MECHANISM OF ACTION Inhibitor
M. Wt 460.53
Formula C24H28N8O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1282512-48-4
Synonyms GDC 0032, GDC0032
SMILES CC1=NN(C(=N1)C2=CN3CCOC4=C(C3=N2)C=CC(=C4)C5=CN(N=C5)C(C)(C)C(=O)N)C(C)C

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