GDC-0068 (Ipatasertib, RG-7440)

Name: GDC-0068 (Ipatasertib, RG-7440)
SKU: A11246
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11246

Akt 抑制剂

GDC-0068 是一种选择性的、ATP竞争性的、全面的Akt抑制剂，它针对Akt1、2和3，在无细胞试验中的IC50值分别为5、18和8 nM。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥525.00	现货
25mg	¥945.00	现货
50mg	¥1,610.00	现货
100mg	¥2,520.00	现货
200mg	¥4,900.00	现货
500mg	¥10,990.00	现货
1g	¥19,075.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

GDC-0068 is a selective, ATP-competitive, pan-Akt inhibitor that targets Akt1, 2, and 3 with IC50 values of 5, 18, and 8 nM, respectively in cell-free assays

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11246
分子式	C24H32ClN5O2
分子量	458
CAS号	1001264-89-6
SMILES	C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O
其他名称	GDC0068, RG7440
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	91 mg/mL (198.69 mM)
	Water	Insoluble
	Ethanol	91 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.83 mL	109.17 mL	218.34 mL
0.5 mM	4.37 mL	21.83 mL	43.67 mL
1 mM	2.18 mL	10.92 mL	21.83 mL
5 mM	0.44 mL	2.18 mL	4.37 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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