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GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.55 mL | 122.74 mL | 245.48 mL |
| 0.5 mM | 4.91 mL | 24.55 mL | 49.1 mL |
| 1 mM | 2.45 mL | 12.27 mL | 24.55 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.91 mL |
*The above data is based on the productmolecular weight 407.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19494 |
|---|---|
| M. Wt | 407.37 |
| Formula | C18H19F2N5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2060571-02-8 |
| Synonyms | RG6114, RG 6114, RG-6114; GDC-0077, GDC0077, GDC 0077 |
| SMILES | C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1 |
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