GDC-0152

Name: GDC-0152
SKU: A14135
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A14135

IAP 拮抗剂

GDC-0152 是一种模拟 第二线粒体激活凋亡酶（Smac）的抑制剂，它能够抑制 凋亡抑制蛋白（IAPs），具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥560.00	现货
10mg	¥840.00	现货
25mg	¥1,575.00	现货
50mg	¥2,520.00	现货
100mg	¥3,780.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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Data Sheet

SDS

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生物活性

Discription

GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14135
分子式	C25H34N6O3S
分子量	498.64
CAS号	873652-48-3
SMILES	CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC
其他名称	GDC0152, GDC 0152
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	98 mg/mL (196.53 mM)
	Water	3 mg/mL (6.01 mM)
	Ethanol	98 mg/mL (196.53 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.05 mL	100.27 mL	200.55 mL
0.5 mM	4.01 mL	20.05 mL	40.11 mL
1 mM	2.01 mL	10.03 mL	20.05 mL
5 mM	0.4 mL	2.01 mL	4.01 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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