GDC-0152

目录号: A14135

IAP antagonist

GDC-0152 Chemical Structure

CAS NO. 873652-48-3

GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity.

库存: 现货

规格 价格 数量
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
50 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 1,350.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity.
Targets
Target Value
MLXBIR3SGki: 14nM
cIAP1-BIR3ki: 17nM
XIAP-BIR3ki: 28nM
cIAP2-BIR3ki: 43nM
XIAP-BIR2ki: 112nM
cIAP2-BIR2ki: 9.6μM
cIAP1-BIR2ki: 14.5μM
In vitro (25°C) DMSO 99 mg/mL (198.54 mM)
Water 3 mg/mL (6.01 mM)
Ethanol 99 mg/mL (198.54 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.05 mL 100.27 mL 200.55 mL
0.5 mM 4.01 mL 20.05 mL 40.11 mL
1 mM 2.01 mL 10.03 mL 20.05 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14135
MECHANISM OF ACTION Antagonist
M. Wt 498.64
Formula C25H34N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 873652-48-3
Synonyms GDC0152, GDC 0152
SMILES CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 GDC-0152 | GDC-0152 供应商 | 订购 GDC-0152 | GDC-0152 价格 | GDC-0152 生产商 | 订单 GDC-0152 | GDC-0152 代理商 | 购买 873652-48-3| 873652-48-3 供应商 | 订购 873652-48-3 | 873652-48-3 价格 | 873652-48-3 生产商 | 订单 873652-48-3 | 873652-48-3 代理商|buy GDC-0152 | GDC-0152 Supplier | purchase GDC-0152 | GDC-0152 cost | GDC-0152 manufacturer | order GDC-0152 | GDC-0152 distributor | buy 873652-48-3| 873652-48-3 Supplier | purchase 873652-48-3 | 873652-48-3 cost | 873652-48-3 manufacturer | order 873652-48-3 | 873652-48-3 distributor
Rewards