GDC-0349

目录号: A11443

mTOR inhibitor

GDC-0349 Chemical Structure

CAS NO. 1207360-89-1

GDC-0349 is under evaluating the Safety and Tolerability in Patients with locally advanced or metastatic solid tumors or non hodgkin's lymphoma.

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
25 mg
¥ 4,500.00
50 mg
¥ 7,800.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GDC-0349 is under evaluating the Safety and Tolerability in Patients with locally advanced or metastatic solid tumors or non hodgkin's lymphoma.
Targets
mTOR PI3Kα
3.8 nM(Ki)~3 μM(Ki)
In vitro DMSO 91 mg/mL (201.08 mM)
Water <1 mg/mL (<1 mM)
Ethanol 6 mg/mL (13.25 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.09 mL 110.47 mL 220.95 mL
0.5 mM 4.42 mL 22.09 mL 44.19 mL
1 mM 2.21 mL 11.05 mL 22.09 mL
5 mM 0.44 mL 2.21 mL 4.42 mL

*The above data is based on the productmolecular weight 452.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11443
MECHANISM OF ACTION Inhibitor
M. Wt 452.6
Formula C24H32N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1207360-89-1
Synonyms GDC 0349, RG7603
SMILES CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CCN(C3)C4COC4)C(=N2)N5CCOC[C@@H]5C

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