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GDC-0575 (ARRY-575, RG7741)

GDC-0575 (ARRY-575, RG7741)

Name: GDC-0575 (ARRY-575, RG7741)
SKU: A16811

目录号: A16811

Chk1 抑制剂

GDC-0575 (ARRY-575, RG7741) Chemical Structure

CAS NO. 1196541-47-5

GDC-0575 (ARRY-575,RG7741)是一种有效的选择性CHK1抑制剂，IC50为1.2 nM。

库存：现货

规格	价格	数量
5 mg	￥ 2,000.00
10 mg	￥ 3,200.00
50 mg	￥ 12,000.00

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GDC-0575 (ARRY-575,RG7741)是一种有效的选择性CHK1抑制剂，IC50为1.2 nM。

溶解度 *

In vitro	DMSO	68 mg/mL (179.76 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (13.21 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.44 mL	132.18 mL	264.36 mL
0.5 mM	5.29 mL	26.44 mL	52.87 mL
1 mM	2.64 mL	13.22 mL	26.44 mL
5 mM	0.53 mL	2.64 mL	5.29 mL

*The above data is based on the productmolecular weight 378.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16811
作用机制	Inhibitor (抑制剂)
M. Wt	378.27
Formula	C16H20BrN5O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1196541-47-5
Synonyms	GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476;
SMILES	O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32