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MEK1 抑制剂

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产品目录号: A12974


产品名 目录号 价格 数量
GDC-0623 5mg A12974-5
¥ 1,400.00
GDC-0623 10mg A12974-10
¥ 2,500.00
GDC-0623 25mg A12974-25
¥ 5,500.00



GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.





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Chemical Information

目录号 A12974
Mechanism of action Inhibitor
分子量 456.21
化学分子式 C16H14FIN4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1168091-68-6
Synonyms GDC0623, GDC 0632
化学名称 5-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide


GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
0.13 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.92 mL 109.6 mL 219.2mL
0.5 mM 4.38 mL 21.92 mL 43.84 mL
1 mM 2.19 mL 10.96 mL 21.92 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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