GDC-0810 (Brilanestrant)

Name: GDC-0810 (Brilanestrant)
SKU: A15958

目录号: A15958

Estrogen receptor degrader

GDC-0810 (Brilanestrant) Chemical Structure

CAS NO. 1365888-06-7

GDC-0810 (Brilanestrant)是一种口服可生物利用的选择性雌激素受体降解剂（SERD），在耐他莫昔芬的乳腺癌异种移植物中表现出强大的活性。

库存：现货

规格	价格	数量
5 mg	￥ 1,300.00
10 mg	￥ 1,950.00
25 mg	￥ 3,800.00

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生物活性

GDC-0810 (Brilanestrant)是一种口服可生物利用的选择性雌激素受体降解剂（SERD），在耐他莫昔芬的乳腺癌异种移植物中表现出强大的活性。

溶解度 *

In vitro	DMSO	82 mg/mL (183.48 mM)
	Water	Insoluble
	Ethanol	82 mg/mL (183.48 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.38 mL	111.88 mL	223.76 mL
0.5 mM	4.48 mL	22.38 mL	44.75 mL
1 mM	2.24 mL	11.19 mL	22.38 mL
5 mM	0.45 mL	2.24 mL	4.48 mL

*The above data is based on the productmolecular weight 446.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15958
作用机制	Degrader (降解剂)
M. Wt	446.91
Formula	C26H20ClFN2O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1365888-06-7
Synonyms	RG6046, ARN-810, ARN810, ARN 810
SMILES	O=C(O)/C=C/C1=CC=C(C=C1)/C(C2=CC3=C(NN=C3)C=C2)=C(CC)\C4=CC=C(C=C4Cl)F