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BTK 抑制剂

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产品目录号: A12706


产品名 目录号 价格 数量
GDC-0834 5mg A12706-5
¥ 1,800.00
GDC-0834 10mg A12706-10
¥ 2,680.00
GDC-0834 25mg A12706-25
¥ 5,000.00
GDC-0834 50mg A12706-50
¥ 7,260.00



GDC-0834 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), investigated as a potential treatment for rheumatoid arthritis.





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Chemical Information

目录号 A12706
Mechanism of action Inhibitor
分子量 596.74
化学分子式 C33H36N6O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1133432-46-8
Synonyms GDC0834, GDC 0834
SMILES code CC1=C(C=CC=C1NC(=O)C2=CC3=C(S2)CCCC3)C4=CN(C(=O)C(=N4)NC5=CC=C(C=C5)C6C(=O)N(CCN6C)C)C
化学名称 (R)-N-(3-(6-((4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenyl)amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide


GDC-0834 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), investigated as a potential treatment for rheumatoid arthritis.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.76 mL 83.79 mL 167.58mL
0.5 mM 3.35 mL 16.76 mL 33.52 mL
1 mM 1.68 mL 8.38 mL 16.76 mL
5 mM 0.34 mL 1.68 mL 3.35 mL

*The above data is based on the productmolecular weight 596.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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