GDC0994 (Ravoxertinib)

Name: GDC0994 (Ravoxertinib)
SKU: A13420
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A13420

ERK1/2 抑制剂

GDC-0994 是一种强效且选择性的 Erk1/2 抑制剂。GDC-0994 抑制 ERK 磷酸化以及 ERK-介导的信号传导途径的激活。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥630.00	现货
25mg	¥1,190.00	现货
50mg	¥2,030.00	现货
100mg	¥3,045.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

GDC-0994 is a potent and selective Erk1/2 inhibitor. GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways.

Targets

Target	Value

产品信息

目录号	A13420
分子式	C21H18ClFN6O2
分子量	440.87
CAS号	1453848-26-4
SMILES	CN1C(=CC=N1)NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)[C@H](CO)C4=CC(=C(C=C4)Cl)F
其他名称	GDC-0994
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	83 mg/mL (188.7 mM)
	Water	Insoluble
	Ethanol	83 mg/mL
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.68 mL	113.41 mL	226.82 mL
0.5 mM	4.54 mL	22.68 mL	45.36 mL
1 mM	2.27 mL	11.34 mL	22.68 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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