Gedivumab (MHAA4549A; RG7745) is a human monoclonal antibody engineered to target the influenza A virus (IAV) with high specificity. It binds to the highly conserved stem region of the IAV hemagglutinin protein. This interaction inhibits hemagglutinin maturation and blocks hemagglutinin-mediated membrane fusion within the intranucleosome. Gedivumab is an essential tool for research in IAV infection disease studies, offering potential insights into viral entry mechanisms and the development of antiviral therapies.
Gedivumab (MHAA4549A; RG7745) is a human monoclonal antibody engineered to target the influenza A virus (IAV) with high specificity. It binds to the highly conserved stem region of the IAV hemagglutinin protein. This interaction inhibits hemagglutinin maturation and blocks hemagglutinin-mediated membrane fusion within the intranucleosome. Gedivumab is an essential tool for research in IAV infection disease studies, offering potential insights into viral entry mechanisms and the development of antiviral therapies.
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