Geldanamycin

目录号: A11025

Hsp90 inhibitor

Geldanamycin Chemical Structure

CAS NO. 30562-34-6

Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
50 mg
¥ 4,000.00
100 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 1,260.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.
Targets
p185 HSP90 (N-terminal domain) HSP90
70 nM0.78 μM(Kd)1.2 μM(Kd)
In vitro DMSO 100 mg/mL heating (178.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.19 mL 178.38 mL
0.5 mM 3.57 mL 17.84 mL 35.68 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11025
MECHANISM OF ACTION Inhibitor
M. Wt 560.6
Formula C29H40N2O9
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 30562-34-6
Synonyms N/A
SMILES C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C/C=C(/C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)\C)OC)OC(=O)N)\C)C)O)OC

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