GEN-1053 (BNT-313) is a fully human monoclonal antibody of the IgG1 subclass, specifically targeting CD27. Upon binding to its antigen, GEN-1053 facilitates the formation of a hexameric structure. For experimental control purposes, Human IgG1 lambda1 serves as the appropriate isotype control for GEN-1053. This antibody is crucial for studies focusing on the modulation of the CD27 signaling pathway, which is significant in immune regulation and has implications in therapeutic interventions for immune disorders and cancers.
GEN-1053 (BNT-313) is a fully human monoclonal antibody of the IgG1 subclass, specifically targeting CD27. Upon binding to its antigen, GEN-1053 facilitates the formation of a hexameric structure. For experimental control purposes, Human IgG1 lambda1 serves as the appropriate isotype control for GEN-1053. This antibody is crucial for studies focusing on the modulation of the CD27 signaling pathway, which is significant in immune regulation and has implications in therapeutic interventions for immune disorders and cancers.
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