Gentulizumab (Gensci-059) is a humanized IgG4 monoclonal antibody specifically designed to target CD47. This antibody demonstrates robust binding affinity for CD47 across both human and monkey tissues, effectively disrupting the CD47-SIRP?? interaction. Such inhibition plays a critical role in modulating antitumor immunity, making Gentulizumab a potent agent for antitumor activity studies. For experimental control purposes, Human IgG4 (S228P) kappa serves as the appropriate isotype control for Gentulizumab.
Gentulizumab (Gensci-059) is a humanized IgG4 monoclonal antibody specifically designed to target CD47. This antibody demonstrates robust binding affinity for CD47 across both human and monkey tissues, effectively disrupting the CD47-SIRP?? interaction. Such inhibition plays a critical role in modulating antitumor immunity, making Gentulizumab a potent agent for antitumor activity studies. For experimental control purposes, Human IgG4 (S228P) kappa serves as the appropriate isotype control for Gentulizumab.
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