Genz-123346 free base
目录号: A15442
GL1 synthase 抑制剂
Genz-123346 free base 是一种 GL1 synthase 抑制剂,它阻断了神经酰胺向 GL1 的转化;对 GM1 抑制的 IC50 为 14 nM。
| Discription | Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; IC50 for GM1 inhibition is 14 nM. |
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| 目录号 | A15442 |
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| 分子式 | C24H38N2O4 |
| 分子量 | 418.57 |
| CAS号 | 491833-30-8 |
| SMILES | CCCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O |
| 其他名称 | Genz123346 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 77 mg/mL (183.96 mM) | |
| Water | Insoluble | ||
| Ethanol | 77 mg/mL (183.96 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.89 mL | 119.45 mL | 238.91 mL |
| 0.5 mM | 4.78 mL | 23.89 mL | 47.78 mL |
| 1 mM | 2.39 mL | 11.95 mL | 23.89 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2