GGTI298
目录号: A20418
GGTase I 抑制剂
GGTI298 是一种 CAAZ 肽类似物的 鲨烯基转移酶 I (GGTase I) 抑制剂,强烈抑制鲨烯基化的 Rap1A 的处理,对法尼基化的 Ha-Ras 的处理影响较小,其 IC50 值分别为 3 和 >20 μM。
Discription | GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively. | |||||
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Cell Research |
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目录号 | A20418 |
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分子式 | C27H33N3O3S |
分子量 | 479.63 |
CAS号 | 180977-44-0 |
SMILES | CC(C)C[C@@H](C(OC)=O)NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=C3C=CC=CC3=CC=C2)=O |
其他名称 | GGTI 298, GGTI-298 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2