Girentuximab (G250) is a chimeric IgG1 monoclonal antibody that selectively binds carbonic anhydrase IX (CAIX), a transmembrane glycoprotein highly expressed in clear cell renal cell carcinoma (ccRCC) and hypoxic tumor environments. It is widely used in tumor imaging, targeted therapy development, and CAIX-related cancer biology studies.
Girentuximab (G250) is a chimeric IgG1 monoclonal antibody that selectively binds carbonic anhydrase IX (CAIX), a transmembrane glycoprotein highly expressed in clear cell renal cell carcinoma (ccRCC) and hypoxic tumor environments. It is widely used in tumor imaging, targeted therapy development, and CAIX-related cancer biology studies.
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