Trusted by 10,000+ Scientists since 2006



NOX1/4 抑制剂

0 Customer Reviews
产品目录号: A14433


产品名 目录号 价格 数量
GKT137831 5mg A14433-5
¥ 900.00
GKT137831 10mg A14433-10
¥ 1,400.00
GKT137831 25mg A14433-25
¥ 3,200.00
GKT137831 10mM * 1mL in DMSO A14433-10mM-D
¥ 1,000.00



GKT137831 is a first in class inhibitor targeting NOX1 and NOX4 enzymes.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14433
Mechanism of action Inhibitor
分子量 394.85
化学分子式 C21H19ClN4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1218942-37-0
Synonyms GKT-137831, GKT 137831
SMILES code CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
化学名称 N/A


GKT137831 is a first in class inhibitor targeting NOX1 and NOX4 enzymes.
110 nM(Ki)140 nM(Ki)


Solubility (25°C)* In vitro DMSO 78 mg/mL heating (197.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.33 mL 126.63 mL 253.26mL
0.5 mM 5.07 mL 25.33 mL 50.65 mL
1 mM 2.53 mL 12.66 mL 25.33 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.




Keywords:购买 GKT137831 | GKT137831 供应商 | 订购 GKT137831 | GKT137831 价格 | GKT137831 生产商 | 订单 GKT137831 | GKT137831 代理商 | 购买 1218942-37-0| 1218942-37-0 供应商 | 订购 1218942-37-0 | 1218942-37-0 价格 | 1218942-37-0 生产商 | 订单 1218942-37-0 | 1218942-37-0 代理商|buy GKT137831 | GKT137831 Supplier | purchase GKT137831 | GKT137831 cost | GKT137831 manufacturer | order GKT137831 | GKT137831 distributor | buy 1218942-37-0| 1218942-37-0 Supplier | purchase 1218942-37-0 | 1218942-37-0 cost | 1218942-37-0 manufacturer | order 1218942-37-0 | 1218942-37-0 distributor