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GKT137831

目录号: A14433
NOX1/4 抑制剂
GKT137831 是一种首创的抑制剂,针对 NOX1NOX4 酶。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥350.00
现货
10mg
¥630.00
现货
25mg
¥1,260.00
现货
50mg
¥2,310.00
现货
100mg
¥3,675.00
现货
500mg
¥8,015.00
现货
1g
¥9,975.00
现货
10mM * 1mL in DMSO
¥385.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用GKT137831发表的1篇文献
  • Chia-Hui Huang, .et al. , Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283
  • 生物活性
    Discription GKT137831 is a first in class inhibitor targeting NOX1 and NOX4 enzymes.
    Targets
    Target Value
    产品信息
    目录号 A14433
    分子式 C21H19ClN4O2
    分子量 394.85
    CAS号 1218942-37-0
    SMILES CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
    其他名称 GKT-137831, GKT 137831
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO Warmed: 72 mg/mL (182.34 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+2% Tween 80+30% PEG 300+ddH2O 8 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.33 mL 126.63 mL 253.26 mL
    0.5 mM 5.07 mL 25.33 mL 50.65 mL
    1 mM 2.53 mL 12.66 mL 25.33 mL
    5 mM 0.51 mL 2.53 mL 5.07 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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