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GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.79 mL | 83.93 mL | 167.87 mL |
| 0.5 mM | 3.36 mL | 16.79 mL | 33.57 mL |
| 1 mM | 1.68 mL | 8.39 mL | 16.79 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.36 mL |
*The above data is based on the productmolecular weight 595.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13423 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 595.71 |
| Formula | C29H37N7O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1320346-97-1 |
| Synonyms | GLPG 0187, GLPG-0187 |
| SMILES | O=C(O)[C@H](CNC1=NC(C)=NC(N2CCC(C3=NC4=C(CCCN4)C=C3)CC2)=C1C)NS(=O)(C5=CC=C(OC)C=C5)=O |
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