Filgotinib (GLPG0634)

Name: Filgotinib (GLPG0634)
SKU: A13162
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A13162

JAK1 抑制剂

1 篇发表文献

GLPG0634 是一种口服可用的、选择性的 JAK1 (Janus kinase 1) 抑制剂，由 Galapagos 公司开发，用于治疗类风湿性关节炎以及可能的其他炎症性疾病。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥525.00	现货
10mg	¥980.00	现货
25mg	¥1,890.00	现货
50mg	¥3,395.00	现货
100mg	¥4,795.00	现货
500mg	¥10,115.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Filgotinib (GLPG0634)发表的1篇文献

Keisuke Nishimura, .et al. , Arthritis Rheumatol., 2015, Apr;67(4):893-902 PMID: 25545152

生物活性

Discription

GLPG0634 is an orally-available, selective inhibitor of JAK1 (Janus kinase 1) being developed by Galapagos for the treatment of rheumatoid arthritis and potentially other inflammatory diseases.

Targets

Target	Value

产品信息

目录号	A13162
分子式	C23H18N6O2
分子量	410.15
CAS号	1206101-20-3
SMILES	c1cc(n2c(c1)nc(n2)NC(=O)C3CC3)c4ccc(cc4)OCc5ccc(nc5)C#N
其他名称	GLPG 0634, GLPG-0634
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	0.09 mg/mL (0.22 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.38 mL	121.91 mL	243.81 mL
0.5 mM	4.88 mL	24.38 mL	48.76 mL
1 mM	2.44 mL	12.19 mL	24.38 mL
5 mM	0.49 mL	2.44 mL	4.88 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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