GLPG2451

Name: GLPG2451
SKU: A18919
Price: 2030 CNY
Rating: 5 (288 reviews)

目录号: A18919

CFTR potentiator

GLPG2451 是一种囊性纤维化跨膜传导调节因子（CFTR）增效剂，它能有效增强在低温下恢复的 F508del CFTR，其半数有效浓度（EC50）为 11.1 纳摩尔。

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Grouped product items
规格	价格	库存
5mg	¥2,030.00	现货
10mg	¥3,605.00	现货
25mg	¥6,860.00	现货
50mg	¥9,485.00	现货
100mg	¥12,985.00	现货
*10mM 1mL in DMSO**	¥2,520.00	现货
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Data Sheet

SDS

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生物活性

Discription	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.

产品信息

目录号	A18919
分子式	C16H16F3N3O5S
分子量	419.38
CAS号	2055015-61-5
SMILES	O=S(C1=CC=C(OC(F)(F)F)C=C1)(C2=CN=C(C(NC[C@@H](O)C)=O)C(N)=C2)=O
其他名称	GLPG 2451, GLPG-2451
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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