Glutaminase is a metabolic enzyme that catalyzes the hydrolysis of glutamine to glutamate, playing a critical role in cellular metabolism. The enzyme exists in two isoforms, GLS and GLS2, which exhibit distinct kinetic, immunologic, and molecular characteristics. Glutaminase is widely utilized in cancer research due to its involvement in tumor metabolism and proliferation, making it a valuable tool for understanding oncogenic processes and developing therapeutic strategies.
Glutaminase is a metabolic enzyme that catalyzes the hydrolysis of glutamine to glutamate, playing a critical role in cellular metabolism. The enzyme exists in two isoforms, GLS and GLS2, which exhibit distinct kinetic, immunologic, and molecular characteristics. Glutaminase is widely utilized in cancer research due to its involvement in tumor metabolism and proliferation, making it a valuable tool for understanding oncogenic processes and developing therapeutic strategies.
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