Glyburide

Name: Glyburide
SKU: A10433

目录号: A10433

K+ channel and CFTR Cl- channel blocker

Glyburide Chemical Structure

CAS NO. 10238-21-8

Glyburide (Glibenclamide) 是一种抗糖尿病化合物，是一类磺脲类药物。

库存：现货

规格	价格	数量
250 mg	￥ 400.00
1000 mg	￥ 550.00
10mM * 1mL in DMSO	￥ 500.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

Glyburide (Glibenclamide) 是一种抗糖尿病化合物，是一类磺脲类药物。

溶解度 *

In vitro (25°C)	DMSO	97 mg/mL (196.35 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+corn oil	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.24 mL	101.21 mL	202.43 mL
0.5 mM	4.05 mL	20.24 mL	40.49 mL
1 mM	2.02 mL	10.12 mL	20.24 mL
5 mM	0.4 mL	2.02 mL	4.05 mL

*The above data is based on the productmolecular weight 494. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10433
作用机制	Blocker (阻断剂)
M. Wt	494
Formula	C23H28ClN3O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	10238-21-8
Synonyms	Glibenclamide
SMILES	COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3