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Glycyl-H 1152 2HCl

ROCK 抑制剂

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产品目录号: A13659

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Glycyl-H 1152 2HCl 1mg A13659-1
¥ 1,500.00
Glycyl-H 1152 2HCl 2mg A13659-2
¥ 2,500.00
Glycyl-H 1152 2HCl 5mg A13659-5
¥ 5,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Glycyl-H 1152 2HCl is a selective and potent ROCK inhibitor (IC50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 uM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.)

Glycyl-H 1152 2HCl

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Chemical Information

目录号 A13659
Mechanism of action Inhibitor
分子量 449.4
化学分子式 C18H24N4O3S2HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 913844-45-8
Synonyms Rho Kinase Inhibitor IV
SMILES code CC1CN(CCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C)C(=O)CN
化学名称 (S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride

生物活性

Description
Glycyl-H 1152 2HCl is a selective and potent ROCK inhibitor (IC50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 uM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.)

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.25 mL 111.26 mL 222.52mL
0.5 mM 4.45 mL 22.25 mL 44.5 mL
1 mM 2.23 mL 11.13 mL 22.25 mL
5 mM 0.45 mL 2.23 mL 4.45 mL

*The above data is based on the productmolecular weight 449.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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