Glycyrrhetinic acid (Enoxolone)

目录号: A10353

15-PGDH inhibitor

Glycyrrhetinic acid (Enoxolone) Chemical Structure

CAS NO. 471-53-4

Glycyrrhetinic acid inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive.

库存: 现货

规格 价格 数量
500 mg
¥ 500.00
2000 mg
¥ 1,600.00
10mM * 1mL in DMSO
¥ 590.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Glycyrrhetinic acid inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive.
Targets
15-hydroxyprostaglandin dehydrogenase
In vitro DMSO 94 mg/mL (199.71 mM)
Water <1 mg/mL (<1 mM)
Ethanol 94 mg/mL (199.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.24 mL 106.22 mL 212.45 mL
0.5 mM 4.25 mL 21.24 mL 42.49 mL
1 mM 2.12 mL 10.62 mL 21.24 mL
5 mM 0.42 mL 2.12 mL 4.25 mL

*The above data is based on the productmolecular weight 470.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10353
MECHANISM OF ACTION Inhibitor
M. Wt 470.7
Formula C30H46O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 471-53-4
Synonyms Enoxolone, Glycyrrhetin, Uralenic acid, Glycyrrhetinate, Arthrodont
SMILES C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

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