GLYX-13 (Rapastinel)
目录号: A13576
NMDAR modulator
GLYX-13 是一种选择性的弱部分激动剂,针对 NMDA 受体 的 甘氨酸位点,目前由 Naurex 公司正在开发,作为治疗抗药性抑郁症的辅助疗法。
Discription | GLYX-13 is a selective weak partial agonist of the glycine site of the NMDA receptor which is under development by Naurex as adjunctive therapy for treatment-resistant depression. |
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目录号 | A13576 |
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分子式 | C18H31N5O6 |
分子量 | 413.47 |
CAS号 | 117928-94-6 |
SMILES | C[C@H]([C@@H](C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H]([C@@H](C)O)C(=O)N)N)O |
其他名称 | GLYX 13, GLYX13 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 79 mg/mL (191.07 mM) | |
Water | 79 mg/mL (191.07 mM) | ||
Ethanol | 79 mg/mL (191.07 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.19 mL | 120.93 mL | 241.86 mL |
0.5 mM | 4.84 mL | 24.19 mL | 48.37 mL |
1 mM | 2.42 mL | 12.09 mL | 24.19 mL |
5 mM | 0.48 mL | 2.42 mL | 4.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2