GM 6001

目录号: A13320

MMP inhibitor

GM 6001

GM 6001 Chemical Structure

CAS NO. 142880-36-2

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 1,060.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).
Targets
Target Value
MMP-8ki: 0.1nM
MMP-9ki: 0.2nM
MMP-26ki: 0.36nM
MMP-1ki: 0.4nM
MMP-2ki: 0.5nM
MMP-12ki: 3.6nM
MMP-7ki: 3.7nM
MMP-14ki: 13.4nM
MMP-3ki: 27nM
In vitro DMSO 78 mg/mL (200.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (20.59 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.74 mL 128.7 mL 257.4 mL
0.5 mM 5.15 mL 25.74 mL 51.48 mL
1 mM 2.57 mL 12.87 mL 25.74 mL
5 mM 0.51 mL 2.57 mL 5.15 mL

*The above data is based on the productmolecular weight 388.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13320
MECHANISM OF ACTION Inhibitor
M. Wt 388.5
Formula C20H28N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 142880-36-2
Synonyms Galardin, Ilomastat, GM-6001
SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC

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