GNE 0723

目录号: A12757

NMDAR modulator

GNE 0723

GNE 0723 Chemical Structure

CAS NO. 1883518-31-7

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.

库存: 现货

规格 价格 数量
1 mg
¥ 3,200.00
5 mg
¥ 9,600.00
10 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.38 mL 106.89 mL 213.78 mL
0.5 mM 4.28 mL 21.38 mL 42.76 mL
1 mM 2.14 mL 10.69 mL 21.38 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12757
作用机制 Modulator (调节剂)
M. Wt 467.78
Formula C16H8ClF6N5OS
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1883518-31-7
Synonyms GNE0723, GNE-0723
SMILES N#C[C@H]1[C@H](C2=C(C(F)(F)F)SC3=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC(N32)=O)C1

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