GNE-207

Name: GNE-207
SKU: A18844
Price: 840 CNY
Rating: 5 (288 reviews)

目录号: A18844

CBP bromodomain 抑制剂

GNE-207 是一种新型、高效、可口服的 CBP 溴结构域抑制剂。GNE-207 具有出色的 CBP 抑制效力（CBP IC50 = 1 nM，MYC EC50 = 18 nM），并且展示了良好的药代动力学特性。

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Grouped product items
规格	价格	库存
1mg	¥840.00	现货
5mg	¥2,450.00	现货
10mg	¥3,990.00	现货
25mg	¥8,050.00	现货
50mg	¥12,810.00	现货
100mg	¥20,545.00	现货
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Data Sheet

SDS

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生物活性

Discription

GNE-207 is a novel, potent, and orally bioavailable inhibitor of the bromodomain of CBP. GNE-207 has excellent CBP potency (CBP IC50?=?1?nM, MYC EC50?=?18?nM), and it exhibits a good pharmacokinetic profile.

Targets

Target	Value

产品信息

目录号	A18844
分子式	C29H30N6O3
分子量	510.6
CAS号	2158266-58-9
SMILES	O=C(NC)C1=NC=C(C2=CC3=C(C=N2)C(C4=NN(C5CCOCC5)C6=C4CN(C(C)=O)CC6)=CC=C3)C=C1
其他名称	GNE207, GNE 207
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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