GNE 2861
目录号: A21697
PAK 抑制剂
GNE 2861 是一种PAK抑制剂,显示出对第二组的选择性。GNE 2861 抑制 PAK4、PAK5 和 PAK6,其 IC50 分别为 7.5、36、126 nM。
Discription | GNE 2861 is a PAK inhibitor that displays group II selectivity. GNE 2861 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively. |
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目录号 | A21697 |
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分子式 | C22H26N6O2 |
分子量 | 406.48 |
CAS号 | 1394121-05-1 |
SMILES | OC1(C#CC2=CC=C3N=C(NCCOC)N(C4=NC(N)=NC=C4)C3=C2)CCCCC1 |
其他名称 | GNE2861, GNE-2861 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2