GNE-317
目录号: A13992
PI3K 抑制剂
GNE-317 是一种强效的 PI3K 抑制剂,能够穿越 血脑屏障;在具有完整血脑屏障的小鼠大脑中显示出对 PI3K 通路 的强效抑制作用。
Discription | GNE-317 is a potent PI3K inhibitor that can cross the Blood?? brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB. | |||||
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Targets |
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Cell Research |
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目录号 | A13992 |
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分子式 | C19H22N6O3S |
分子量 | 414.48 |
CAS号 | 1394076-92-6 |
SMILES | COC1(COC1)C2=C(C)C3=C(S2)C(N4CCOCC4)=NC(C5=CN=C(N)N=C5)=N3 |
其他名称 | GNE317, GNE 317 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 40 mg/mL (96.5 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.13 mL | 120.63 mL | 241.27 mL |
0.5 mM | 4.83 mL | 24.13 mL | 48.25 mL |
1 mM | 2.41 mL | 12.06 mL | 24.13 mL |
5 mM | 0.48 mL | 2.41 mL | 4.83 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2