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GNE-317

PI3K 抑制剂

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产品目录号: A13992

库存状态:中国现货中国现货

产品名 目录号 价格 数量
GNE-317 5mg A13992-5
¥ 900.00
GNE-317 10mg A13992-10
¥ 1,400.00
GNE-317 50mg A13992-50
¥ 4,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

GNE-317 is a potent PI3K inhibitor that can cross the Blood brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.

GNE-317

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Chemical Information

目录号 A13992
Mechanism of action Inhibitor
分子量 414.48
化学分子式 C19H22N6O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1394076-92-6
Synonyms GNE317, GNE 317
SMILES code COC1(COC1)C2=C(C)C3=C(S2)C(N4CCOCC4)=NC(C5=CN=C(N)N=C5)=N3
化学名称 5-(6-(3-methoxyoxetan-3-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

生物活性

Description
GNE-317 is a potent PI3K inhibitor that can cross the Blood brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.
Targets
PI3K

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.13 mL 120.63 mL 241.27mL
0.5 mM 4.83 mL 24.13 mL 48.25 mL
1 mM 2.41 mL 12.06 mL 24.13 mL
5 mM 0.48 mL 2.41 mL 4.83 mL

*The above data is based on the productmolecular weight 414.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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