GNE 477

目录号: A14114

PI3K/mTOR inhibitor

GNE 477 Chemical Structure

CAS NO. 1032754-81-6

GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.

库存: 现货

规格 价格 数量
2 mg
¥ 900.00
5 mg
¥ 1,700.00
10 mg
¥ 2,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.82 mL 99.08 mL 198.16 mL
0.5 mM 3.96 mL 19.82 mL 39.63 mL
1 mM 1.98 mL 9.91 mL 19.82 mL
5 mM 0.4 mL 1.98 mL 3.96 mL

*The above data is based on the productmolecular weight 504.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14114
MECHANISM OF ACTION
M. Wt 504.64
Formula C21H28N8O3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1032754-81-6
Synonyms GNE-477,GNE477
SMILES CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)S(=O)(=O)C

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