GNE0877
目录号: A13969
LRRK2 抑制剂
GNE-0877 是一种高效且选择性的 LRRK2 抑制剂。
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生物活性
| Discription | GNE-0877 is a highly potent and selective LRRK2 inhibitor. | ||
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| Targets |
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产品信息
| 目录号 | A13969 |
|---|---|
| 分子式 | C14H16F3N7 |
| 分子量 | 339.31895 |
| CAS号 | 1374828-69-9 |
| SMILES | CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N |
| 其他名称 | GNE-0877, GNE 0877, GNE0877 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 63 mg/mL (185.66 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.47 mL | 147.35 mL | 294.71 mL |
| 0.5 mM | 5.89 mL | 29.47 mL | 58.94 mL |
| 1 mM | 2.95 mL | 14.74 mL | 29.47 mL |
| 5 mM | 0.59 mL | 2.95 mL | 5.89 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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